Week 1 delivered a high-octane start to fantasy football, headlined by Bills vs. Ravens in a 41-40 thriller. Allen crushed with 42.8 fantasy points and Lamar Jackson posted 33.4 in a game where Bills dominated time of possession. Zay Flowers carved out a major role with nine targets for 143 yards and a TD, while Keon Coleman piled up 11 targets and meaningful late-game production. Andrews’ lone target raised eyebrows, but the Bills’ aerial volume, plus Cook’s red-zone usage, kept rosters buzzing for Week 2.

Marvin Harrison Jr. stood out in Indy, while CJ Stroud and Nico Collins flashed, Nico’s volume remains a fixture amid Texans’ line concerns. Kyler Murray and Jaxon Smith-Njigba showcased elite talent in Green Bay and Seattle respectively, and Puka Nacua’s early-season path is already clear. Week 1 highlighted target distribution, volatility, and the big-week upside that can drive fantasy lineups all season.

Rams face week one with corner depth in flux as Ahkello Witherspoon misses practice, pushing Ahkello’s backing duo into bigger roles and elevating Emanuel Forbes Jr. and Kobe Durant. Houston’s Nico Collins looms as a major test, while CJ Stroud leans on quick-developing throws to gain early footing.

Stafford’s health remains a key risk factor with Devonte Adams stepping in as a primary playmaker alongside Puka Nacua, Kyron Williams handling the ground game. Rams’ edge and front line must neutralize Will Anderson and the Texan front to open the season with control.

Early week intrigue centers on whether Stafford is truly ready and how Adams and the revamped WR corps translate against Houston, with a looming Eagles test in Week 2 providing a real barometer for fantasy ceilings across Rams skill-position players.